Restylane and RHA are hyaluronic acid fillers that can be injected into areas with volume loss. As we age, our skin, muscle, fat and bone change and contribute to a loss of volume and support, therefore resulting in the appearance of deeper wrinkles and sagging skin. Filler can be injected into the face and hands to improve the appearance of lines and volume loss. The most common areas for filler are cheeks, lips, jaw, chin, nasolabial folds and marionettes. Most hyaluronic acid fillers last between 9 and 15 months.